Machine building is still attractive for investment - high intellectual potential of engineers, skilled personnel, production areas provide the opportunity to implement various projects, besides, multipurpose equipment can be used not only for machine building production.

Machine building enterprises produce over 10% of the regional industrial output. The leading companies of this sector are Chelyabinsk Tractor Plant Uraltrac, Chelyabinsk Construction and Road Machinery, Kopeysk Machine Building Plant, Chelyabinsk Mechanical Plant, Ural Automobile Plant, Chelyabinsk Forge-and-Press Plant, Ust-Katav Car Building Plant, Miasselektroapparat, Teplopribor Plant, Metran Industrial Group, Chelyabinsk Electrode Plant, etc.

The most important objectives of the machine building industry are to preserve and develop technical and scientific potential, increase the output of value added goods, use the most valuable elements of industrial, scientific, and technological potential of defense machine building for modernization of civil machine building.

In the North-West of the region there are unique largest atomic centres (Snezhinsk and Ozersk cities), in the West there are centres of rocket engineering and space machinery.